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Senior Software Engineer
TetraScience · Full-time
Aug 2022 - Present
• 2 yrs 9 mos![]()
Senior Bioinformatics Engineer
Personalis, Inc.
Apr 2021 - Aug 2022
• 1 yr 5 mos![]()
Genentech
Jun 2014 - Apr 2021
Data Scientist
Apr 2020 - Apr 2021
• 1 yr 1 mo* Used Python (scikit-learn/keras/tensorflow) and R-based (tidyverse/caret) chemometric, statistical, and machine learning approaches for automated analytics of mass spectrometry, spectroscopic, and chromatographic datasets for biotherapeutic and bioprocess characterization.
* Developed R libraries and GCP-based analytics service (Storage/BigQuery/Notebooks) to analyze the linkage of biotherapeutic CQAs with clinical data to support control system specifications.
* Developed deep neural networks and deployed them to a streaming GCP data pipeline (IoT Core/PubSub/CloudFunctions/AI Model Prediction) to simulate and monitor bioprocess activity.
* led a team of chemists, engineers, and data scientists to develop and deploy GCP data pipelines for automated processing, analysis, and results storage for near-real-time assessment of ion-exchange chromatograms (IoT Core/PubSub/CloudFunctions/AI Model Prediction/graphQL/Django/Postgres)
Data Engineer
Dec 2015 - Apr 2020
• 4 yrs 5 mos* Identified opportunities for digital transformation in a protein chemistry department, proposed and led software engineering or data science projects to improve scientific insight and research efficiency.
* Led teams of up to five and managed projects in all phases of the software development life cycle from requirements gathering to maintenance.
* Key technical contributions: Established genetic algorithm based AI for ML model optimization in Raman Spectroscopy. Developed machine learning models for deep sequencing and sequence variant analysis. Created R Shiny web applications to process and interpret Sanger Sequencing data. Developed R libraries and scripts for analysis of NGS, MS, Raman Spectrscopy data.
Bioinformatics Associate / Scientific Software Specialist
Jun 2014 - Dec 2015
• 1 yr 7 mos* Supported non-clinical biomarker technology platform for exploratory research with software requirements gathering and design specifications. Proposed new software features for biomarker development.
* Assisted Oracle database schema analysis and design. Authored software design documentation and requirements.
* Created interactive Spotfire data visualizations for effective scientific analysis of large data. Primary computer languages: R, SQL, Python.
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Quality Engineer
Micropoint Bioscience, Inc.
Sep 2012 - Jun 2014
• 1 yr 10 mos* Bioinformatic processing of structured and unstructured scientific data from ETL to analysis.
* Characterization, validation, design, optimization, and analysis of medical devices and experiments.
* Specialization on experimental design, quality and business systems design, protocol/ report writing.
* Specialization in statistics, specifically multiple comparisons, regression, data visualization.
* SOP/WI writing for business procedures, quality processes, and scientific experiments.
* Developed QC checks and calibration methods for lateral flow immunoassay technologies.
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Cell Culture Manufacturing Associate
Boehringer Ingelheim
Jan 2012 - Sep 2012
• 9 mos* Assisted mammalian cell culture growth from 100-L to 12,000-L scale bioreactors. Multiproduct pharmaceutical production experience with CHO cells, Good Documentation Practices, and Good Manufacturing Practices.
* In-Process responsibilities including biotreactor setup/tear-down, batching and transfers, monitoring, CIPs, SIPs, and cell culture harvest. Troubleshooting experience with bioreactor and equipment malfunctions.
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Laboratory Assistant
Spectra Laboratories / ATR International
Dec 2011 - Feb 2012
• 3 mosRequisition processing using LIS-CRT. Preparation of blood, urine, and dialysate samples for chemical, bacterial, hematological, and immunological testing. Specimen preps, MLK2/OLA operation, and SOPs in a biomedical laboratory.
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Student Laboratory Assistant
Scripps Institute of Oceanography
Mar 2009 - Sep 2011
• 2 yrs 7 mosPerformed microscopy-based characterization of marine mesozooplankton, and conducted latitudinal and longitudinal statistical analysis of biogeographical data. Acting lab manager, performed design of experiments, equipment and inventory management. Led an undergraduate research team, identified and implemented process improvements.
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Laboratory Assistant
UCSD Department of Biology
Oct 2010 - Jun 2011
• 9 mosThe focus of our group is to study the genetic diversity of the biofuel crop, Jatropha curcans. Our work concentrated on the diversity of microsatellite repeats in J. curcas' genome, and my role was to extract and purify DNA, amplify microsatellite sequences and resolve DNA bands on high resolution gel electrophoresis machines, in addition to working on procedures to perfect J. curcans cloning processes.
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Executive Manager
College Works Painting
Mar 2007 - Sep 2008
• 1 yr 7 mosStarted up a small house painting business, where I marketed my business to local homeowners, sold contracts up to $7,200 value, hired and inspired work crews, and managed inventory for a complex production schedule.